Anthropic's $65B Run Rate: 3 Stocks to Profit

Anthropic, the company behind the Claude chatbot, has reportedly reached an annualized revenue run rate of $65 billion, a sevenfold increase from the end of last year. This explosive growth has prompted the company to file for an IPO, which could value it at $2 trillion or more.

Because Anthropic is still private, retail investors can't buy shares directly. However, several public companies have invested heavily in Anthropic, giving their shareholders indirect exposure to its success.

Amazon leads the pack with a $33 billion investment, holding a 21% stake. Alphabet, Google's parent, owns 15%, while Salesforce has invested $5 billion. Zoom Communications also holds a smaller $1.3 billion stake.

These stakes could become significantly more valuable if Anthropic's IPO meets expectations. The precedent is clear: Alphabet and Amazon both booked massive gains from their stakes in SpaceX and Anthropic, respectively, in recent quarters.

Amazon's shares soared after it reported a $53.4 billion income from revaluing its Anthropic investment. A successful IPO could trigger another revaluation, benefiting shareholders of these tech giants.

For investors, the key takeaway is that owning shares of Amazon, Alphabet, or Salesforce offers a way to profit from Anthropic's growth without direct exposure. If Anthropic's IPO values the company at $2 trillion, these stakes could be worth substantially more, potentially boosting the parent companies' earnings and stock prices.

Amazon's 21% stake is the most significant, and the company has already demonstrated how such investments can drive earnings. Alphabet's 15% stake is also substantial, though its stock has lagged in 2026 due to broader AI spending concerns.

Salesforce's $5 billion stake is smaller but still meaningful, especially given its stock's 22% decline this year. The potential upside from Anthropic could offset some of the pessimism surrounding its core software business.

However, these gains are not guaranteed. IPO valuations can be volatile, and the tech sector faces headwinds from AI infrastructure costs. Investors should weigh the potential upside against these risks.

Overall, this news highlights the interconnected nature of the AI industry and the opportunities for indirect investment through established tech giants.